A new drug that attacks a variety of cancers by starving the tumors' blood supplies will be tested on humans for the first time in a new trial in the UK, it was announced Wednesday.
Scientists at the Mount Vernon Cancer Center, in London, plan to recruit 40 patients with advanced tumors for the Phase I trial of the drug, L-NNA, to establish the correct dose.
L-NNA works by blocking a protein called nitric oxide synthase (NOS), which constricts the vessels supplying blood to cancers and may also prevent the growth of new blood vessels.
Professor Peter Hoskin, from the center, said, "All cancers rely on the delivery of vital nutrients and oxygen through blood vessels—without a blood supply, a tumor can't grow beyond the size of a pin head."
He added, "Scientists across the world are looking for ways to prevent cancer cells from receiving the supplies they depend on to grow and divide. It's very exciting to launch this trial of a new drug, which in the future may provide a new approach to treat a wide range of cancers."
The trial will be funded by Cancer Research UK's Drug Development Office.
Dr. Nigel Blackburn, director of drug development at the charity, said, "This is a promising area of research—there are already drugs available which can reduce the growth of blood vessels being used to treat people with certain types of cancer—and we're looking forward to the early trial results of this new drug with great interest."
Read more: http://www.foxnews.com/health/2011/11/02/new-cancer-drug-that-starves-tumors-blood-supply-to-be-tested/#ixzz1cZ8jnANw
bravo keeping my fingers crossed that it does work ...
Surely a cure for cancer cannot be too far off these days?
We've been hearing that for many years, but unfortunately the stats show that 40% of adult deaths are due to cancer. Much progress has been made, but an absolute cure would be a dream come true for so many patients and their loved ones.
... my mom included.....
:nono1:
I read somewhere on a conspiracy board, that the big medical companies already have/had a cure decades ago, but it was in their financial interests not to market the medication has they were/are making tons of money on the medications/treatment currently available.....
It's just a theory, but does however make one wonder.... we can put a man on the moon, but cannot cure cancer..... We can transplant Organs but can't cure cancer.....
Mmmh!
Just my 2 cents....
Michael what about the common cold!!............ this one takes in billions of dollars with so called cures, do you think they will cure it................... image14
Dr Holt Radiowave Therapy
Introduction
Thank you for visiting Dr John Holt's web pages.
Dr Holt greatest accomplishment, and that for which he is best known, is his innovation of two unique forms of radiowave therapy for the treatment of cancer.
Dr Holt retired from practicing medicine and treating people with his unique cancer therapies, in 2004. However, the legacies he leaves the community are significant. Dr Holt is a very modest cancer treatment innovator. He spent his life saving peoples lives and his inquisitive and inventive mind led him on a journey into very forward thinking theories about causes of cancer and ways to treat it.
Dr Holt treated thousands of persons with Radiowave Therapy, and when he retired at 80 years of age, he passed his treatment methods, systems and processes to the Radiowave Therapy Clinic and to the Radiowave Therapy Research Institute. More >
Radiowave Therapy – The Debate
This web site is sponsored by former patients of Dr Holt. Along with the aims stated on this page, this site remains dedicated to ensuring that those with cancer remain informed about radiowave therapy, including the progress of research and results thereof.
An enormous amount of information about cancer and how to cure it is accessible through the web. One factor with this is that it is hard to know what and who to rely on. This can lead to anxiety and confusion for some, especially if they are having a treatment and it does not appear to be delivering the expected results. It is not so much a matter of trust in what you read or what your medical advisor tells you, it is more that we are inherently nervous about exactly what is best.
So what is best for you? Sadly there is no perfect treatment for cancer. There are plenty of web sites criticising conventional treatments, but the reality for many types of cancer is that conventional treatments have known statistical results, and therefore can be exactly the right option. For some however, conventional treatments can be a journey of ever diminishing returns with a pretty confronting future.
So perhaps the answer to the question of 'what is best' is more likely to be found in making sure that one has the knowledge necessary to participate in their treatment decisions. At least this would limit confusion and anxiety and bring to a person a sense of control over their future. More
www.holtclinic.com is a site dedicated to Dr Holt
Indeed Frank! The common cold.... and don't forget the water engine, car engine that runs on water......
Can't place the name of the documentary right now.....
This is another cure for some 'ONCOTICE' BCG it was found to be a cure for tuberculosis and Cancer.
The history of BCG is tied to that of smallpox. Jean Antoine Villemin first recognized bovine tuberculosis in 1854 and transmitted it, and Robert Koch first distinguished Mycobacterium bovis from Mycobacterium tuberculosis. After the success of vaccination in preventing smallpox, scientists thought to find a corollary in tuberculosis by drawing a parallel between bovine tuberculosis and cowpox: It was hypothesized that infection with bovine tuberculosis might protect against infection with human tuberculosis. In the late 19th century, clinical trials using M. bovis were conducted in Italy with disastrous results, because M. bovis was found to be just as virulent as M. tuberculosis.
Institut Pasteur de Lille
(http://upload.wikimedia.org/wikipedia/commons/thumb/0/09/LouisPasteurMonumentLille.jpg/150px-LouisPasteurMonumentLille.jpg)
Albert Calmette, a French bacteriologist, and his assistant and later colleague, Camille Guérin, a veterinarian, were working at the Institut Pasteur de Lille (Lille, France) in 1908. Their work included subculturing virulent strains of the tubercle bacillus and testing different culture media. They noted a glycerin-bile-potato mixture grew bacilli that seemed less virulent, and changed the course of their research to see if repeated subculturing would produce a strain that was attenuated enough to be considered for use as a vaccine. The research continued throughout World War I until 1919, when the now avirulent bacilli were unable to cause tuberculosis disease in research animals. They transferred to the Paris Pasteur Institute in 1919. The BCG vaccine was first used in humans in 1921.
Public acceptance was slow, and one disaster, in particular, did much to harm public acceptance of the vaccine. In the summer of 1930 in Lübeck, 240 infants were vaccinated in the first 10 days of life; almost all developed tuberculosis and 72 infants died. It was subsequently discovered that the BCG administered had been contaminated with a virulent strain that was being stored in the same incubator, and led to legal action being taken against the manufacturers of BCG.
Cancer immunotherapy: BCG is used in the treatment of superficial forms of bladder cancer. Since the late 1980s, evidence has become available that instillation of BCG into the bladder is an effective form of immunotherapy in this disease. While the mechanism is unclear, it appears a local immune reaction is mounted against the tumor. Immunotherapy with BCG prevents recurrence in up to 67% of cases of superficial bladder cancer. BCG also finds use for immunotherapy of colorectal cancer and for the treatment of equine sarcoid in horses. A number of cancer vaccines in development use BCG as an adjuvant to provide an initial stimulation of the patients' immune system.
There are a lot of cancers out there. giverose